导师类型:硕士生导师
单 位:05中药研究所
出生年月:1983年12月
专业职务:副研究员
学 位:医学博士
毕业学校:中国中医科学院
第一学科:中药学
第二学科:中药学
研究方向:中药复方药理与配伍机制;中医药信息学
联系电话:13439071675
邮 箱:bli@icmm.ac.cn
邮 编:100700
联系地址:北京市东城区东直门内南小街16号
个人简介:中医学博士,中西医结合专业博士后,中国中医科学院中药研究所副研究员,兼任世界中医药学会联合会网络药理学专业委员会、临床数据监察工作委员会常务理事、中国中医药信息学会名医传承信息化分会理事。主要从事中药复方药理、中药配伍与组方机制、中医药信息学等相关研究工作。主持或主要参与国家自然科学基金、“重大新药创制”科技重大专项、国家重点研发计划等部局级以上科研课题10余项,在Briefings in Bioinformatics, Molecular Therapy-Nucleic Acids, Scientific Reports, Frontiers in Pharmacology, EBioMedicine,Clinical and Translational Medicine,acta pharmacologica sinica等国内外学术期刊发表论文100余篇,其中SCI收录30余篇,参编著作12部,获发明专利2项、软件著作权15项。相关研究获中国中西医结合学会科学技术奖一等奖1项、中华中医药学会科技进步二等奖1项、中国中医科学院科技进步一、二等奖各1项。
论文:
TCMFP: a novel herbal formula prediction method based on network target’s score integrated with semi-supervised learning genetic algorithms Briefings in Bioinformatics 2023/1/19
A Molecular Classification of Gastric Cancer Associated with Distinct Clinical Outcomes and Validated by an XGBoost-Based Prediction Model Molecular Therapy-Nucleic Acids 2022/12/30
古代经典名方功能主治考证原则与建议 中国中药杂志 2021/4/1
网络象思维特征与前景分析 北京中医药大学学报 2020/7/1
Quantitative assessment of gene expression network module-validation methods Scientific Reports 2015/9/1
Vertical and Horizontal Convergences of Targeting Pathways in Combination Therapy with Baicalin and Jasminoidin for Cerebral Ischemia CNS & Neurological Disorders Drug Targets 2016/6/1
Network-wide Screen Identifies Variation of Novel Precise On-module Targets Using Conformational Modudaoism CPT:PSP 2017/7/1
Optimizing miRNA-module diagnostic biomarkers of gastric carcinoma via integrated network analysis PLoS ONE 2018/6/1
Gene Expression Profiling Confirms the Dosage-Dependent Additive Neuroprotective Effects of Jasminoidin in a Mouse Model of Ischemia-Reperfusion Injury Biomed Research International 2018/12/1
专著:
中医药临床大数据研究 中国医药科技出版社
中医证候现代研究理论与实践 人民卫生出版社
获奖:
TCMFP: a novel herbal formula prediction method based on network target’s score integrated with semi-supervised learning genetic algorithms Briefings in Bioinformatics
A Molecular Classification of Gastric Cancer Associated with Distinct Clinical Outcomes and Validated by an XGBoost-Based Prediction Model Molecular Therapy-Nucleic Acids
古代经典名方功能主治考证原则与建议 中国中药杂志
网络象思维特征与前景分析 北京中医药大学学报
Quantitative assessment of gene expression network module-validation methods Scientific Reports
Vertical and Horizontal Convergences of Targeting Pathways in Combination Therapy with Baicalin and Jasminoidin for Cerebral Ischemia CNS & Neurological Disorders Drug Targets
Network-wide Screen Identifies Variation of Novel Precise On-module Targets Using Conformational Modudaoism CPT:PSP
Optimizing miRNA-module diagnostic biomarkers of gastric carcinoma via integrated network analysis PLoS ONE
Gene Expression Profiling Confirms the Dosage-Dependent Additive Neuroprotective Effects of Jasminoidin in a Mouse Model of Ischemia-Reperfusion Injury Biomed Research International